23andMe raw data
A health report from the 23andMe file you already own.
MarkerView reads the raw data file 23andMe lets you download and returns one plain-English PDF: what your covered markers say, how they line up with the medications and supplements you list, and what is worth raising at your next appointment. No new kit, no saliva sample, no subscription. $10 once, or $20 once for the full review.
No new kit · No subscription · Self-service account/data deletion
The file itself
Your 23andMe raw data file
The raw download is a plain text file, delivered zipped. Each line is one marker: an rs identifier, a chromosome, a position, and the letters called at that spot. Chromosomes appear as 1 to 22, X, Y and MT, and positions where the chip could not make a call appear as --. Here are the four steps to download it if you have not yet.
- We read the bytes, not the file name. On upload the server reads the first 2 KB and requires the 23andMe marker in the comment block plus the rsid, chromosome and position column names. A file that merely mentions 23andMe, such as an ancestry composition export, is turned away with instructions before you pay rather than failing after checkout.
- .txt or .zip, exactly as downloaded. Upload the archive and we open it and read the largest text file inside, so you never unzip anything. One order has to fit under 30 MB combined, and the zip is far smaller than the extracted text.
- Both 23andMe layouts are read. The ordinary export is four columns with a single genotype field; 23andMe also ships a five-column phased export. Column width comes from the file's own commented-out header row, or from the most common row width in a sample — never from the vendor name.
- The genome build is handled for you. The file lists genotype letters against the older reference build and carries no reference or alternate allele, so MarkerView looks each rs identifier up in dbSNP build 150 for current-build coordinates and alleles and ignores your file's own chromosome and position columns. A marker whose identifier is not in that reference is not analysed.
- Some rows are dropped, on purpose. No-calls, insertion and deletion markers, and 23andMe's internal “i” identifiers are skipped rather than guessed at. What we accept, and what we refuse lists every case.
One practical note: after 23andMe's 2025 bankruptcy filing, several state attorneys general published consumer alerts on deleting genetic data, noting that customers can download a copy of it first (Minnesota Attorney General, 12 June 2025). If you kept that download, it still works here. MarkerView never connects to 23andMe: we read the file you upload, and nothing else.
What you get
What is in the report
One PDF, emailed to you and waiting in your dashboard. It opens on a single-page handoff — at most three things worth acting on — then works through your data and its limits, medication interaction review, lab results, polygenic and preventive context, what is worth measuring directly, pharmacogenomics, evidence-based genetic associations, wellness and next steps, supplements, and an appendix of unconfirmed rare-variant calls. Sections with nothing to say say so; a section with no content is dropped rather than padded. See the layout, page by page.
| From a 23andMe file | Basic — $10 once | Comprehensive — $20 once |
|---|---|---|
| Your 23andMe raw data file | Yes | Yes |
| Medications and supplements you list, read together | Not included | Yes |
| Optional PDF of recent Quest or Labcorp resultsThose two providers only. | Not included | Yes |
| Merge with one AncestryDNA fileExactly one file from each vendor. | Not included | Yes |
This is a separate reading of the same file, not a replacement for anything 23andMe shows you in your account, and we are not affiliated with them. What it adds is the context a DNA-only reading cannot have: the medicines and supplements you actually take, an optional lab PDF read against your genetics rather than in isolation, and a second vendor's file merged in when you have one. If you also tested with Ancestry, the AncestryDNA page covers that file; the general raw-DNA page covers both.
Read this first
What a 23andMe file cannot tell you
- An array is not sequencing. Your file reports a fixed set of pre-chosen positions, so a gene can be covered partially or not at all. “Nothing notable found” means nothing was found among the markers your chip covered. It is not an all-clear, and not a substitute for the screening your clinician recommends.
- Markers go missing, and we say which. No-calls, insertion and deletion markers, internal identifiers and rs identifiers absent from the reference are all dropped. Insertions, deletions, copy-number and structural variants are not analysed at all.
- Rare, alarming calls are treated as suspect. In a 2018 clinical-laboratory study of variants patients brought in from raw direct-to-consumer data, 40% turned out to be false positives (Tandy-Connor et al., Genetics in Medicine, 2018). MarkerView therefore never headlines a rare pathogenic call; it goes to an appendix, framed for one action: a conversation with a clinician about confirmatory testing.
- This is not a diagnosis. MarkerView is informational. No clinician reviews your individual report, nothing here rules a condition in or out, and nothing here is a reason to start, stop or change a medicine or supplement on your own.
Three steps
From your file to your report
1
Upload the file
Drop in the .txt or .zip you downloaded. We check the format while it is still in front of you, and an unsupported file is turned away without a charge.
2
Add what you take
On Comprehensive, type in every prescription, vitamin and powder, attach a recent Quest or Labcorp PDF if you have one, and add your other vendor's file if you tested twice.
3
Read it, then bring it
The PDF arrives by email and in your dashboard, usually within a couple of hours. It is yours to keep, print and hand to your physician. The longer walkthrough.
Where the findings come from
Sourced, not asserted
Marker mappings come from curated public clinical databases and industry-standard open-source annotation tools. Drug–gene findings name the guideline behind them — CPIC or PharmGKB — with its PubMed identifier, and a finding with no guideline behind it is labelled as such rather than dressed up. Classification, filtering and the safety rules are ordinary deterministic code; where the report needs a sentence of prose, an AI writing model drafts it and the sentence is rejected, not quietly rewritten, if it carries a statistic, a dose or advice. The full method.
Two things worth knowing
What the evidence says about raw-data findings
The number
Of the variants patients brought to a clinical laboratory after finding them in raw direct-to-consumer data, 40% were false positives on confirmation.
Tandy-Connor S, Guiltinan J, Krempely K, et al. Genetics in Medicine 2018;20:1515–1521. PMID 29565420.The standard
The U.S. Food and Drug Administration tells consumers to talk to their health care provider about next steps after a direct-to-consumer genetic health risk result,
“including getting confirmatory genetic testing, if applicable.”U.S. Food and Drug Administration, Direct-to-Consumer Tests.
That is why the report is shaped the way it is: common, well-studied markers are where a consumer array is worth reading, and rare alarming ones belong in a conversation about a confirmatory test, not on page one.
Your data
What happens to the file after you upload it
Your file is encrypted in transit and at rest. You can delete your account and everything in it yourself, from Settings, at any time — no email request, no waiting period (delete your data). We never sell data that identifies you; if de-identified data is ever shared for research we will say so plainly first. What we do with genetic data, and the full trust answers, including where GINA's protections stop.
23andMe questions
Questions people ask about the 23andMe file
Does my chip generation matter?
Different 23andMe chips cover different markers, so what appears in your report depends on what is in your file. MarkerView does not detect or record which generation produced it, and never promises that a particular marker will be in there. The report says what it found and what it could not see.
Can I combine it with my AncestryDNA file?
Yes, on Comprehensive: exactly one file from each vendor. Two files from the same company are refused, and so is the same file twice. Before merging we check that the two overlap on at least 10,000 usable markers and agree on at least 97% of them; if they do not, we stop the run rather than blend two people's results. That is a consistency check on two files, not identity verification. Markers where the two disagree are dropped, and if the second file cannot be parsed at all the report is built from the first with the shortfall stated in it.
I closed my 23andMe account. Can I still use the file?
Yes, if you kept the download. MarkerView reads the file you upload; it never signs in to 23andMe and holds no connection to your account there, so closing it does not affect a report you have already run.
Should I upload the .zip or the .txt?
Either works, exactly as it was downloaded. The zip is easier: we read the largest text file inside it, and an order has to fit under 30 MB combined, which the zip comfortably does. Do not re-zip it yourself with the file renamed.
Do I need a subscription for this?
Not on our side. MarkerView is a one-time purchase, $10 or $20, with no membership, no renewal and no recurring charge. All you need from 23andMe is the raw data download itself.
You already paid for the file. This is what it can tell you.
$10 for the DNA report. $20 for DNA, medications, supplements and lab work reviewed together.
References
- U.S. Food and Drug Administration. Direct-to-Consumer Tests. fda.gov/medical-devices/in-vitro-diagnostics/direct-consumer-tests
- Tandy-Connor S, Guiltinan J, Krempely K, LaDuca H, Reineke P, Gutierrez S, Gray P, Tippin Davis B. False-positive results released by direct-to-consumer genetic tests highlight the importance of clinical confirmation testing for appropriate patient care. Genetics in Medicine 2018;20:1515–1521. PMID 29565420. europepmc.org/article/MED/29565420
- The Jackson Laboratory. Clinical confirmation of consumer genomic test results: a variant of suspected clinical interest “should be clinically confirmed before making any medical decisions”. jax.org
- Minnesota Attorney General. Attorney General Ellison issues updated consumer alert about 23andMe bankruptcy, data deletion, 12 June 2025. ag.state.mn.us
- MarkerView. Science & sources, supported files, genetic data privacy.
23andMe is a trademark of 23andMe, Inc.; AncestryDNA is a trademark of its owner. MarkerView is not affiliated with, endorsed by, or sponsored by either company; it reads the raw data file those services let you download.