ACE
Renal System · Renin-Angiotensin-Aldosterone System
How does ACE participate in blood-pressure regulation?
ACE makes an enzyme that converts angiotensin I into angiotensin II. This is part of a hormone system that coordinates blood-vessel behavior and salt and fluid balance.
- Common Gene Name
- angiotensin I converting enzyme
- NCBI Gene ID
- 1636
- Chromosome
- 17
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| renal tubular dysgenesis - ACE | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2024-12-11 |
| Renal tubular dysgenesis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2013-05 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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