ADAR

Metabolic System · Purine & Pyrimidine Metabolism

Can the body edit an RNA message after making it?

ADAR produces an enzyme that changes adenosine to inosine within selected RNA molecules. This editing helps regulate RNA behavior and the innate immune response.

Common Gene Name
adenosine deaminase RNA specific
NCBI Gene ID
103
Chromosome
1

Clinical Evidence Status

Established disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (4 records)
Condition or drugEvidenceGrade / statusContextSource
Leigh syndromeClinGen gene-disease validityLimitedAutosomal recessiveView source
2020-08-27
ADAR-related type 1 interferonopathyClinGen gene-disease validityDefinitiveAutosomal recessiveView source
2024-10-31
ADAR-related type 1 interferonopathyClinGen gene-disease validityDefinitiveAutosomal dominantView source
2024-10-21
Aicardi-Goutières syndromeMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2024-09

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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