AICDA
Immune System · B-Cell Receptor Signaling & Antibody Repertoire
How do immune cells improve and change the antibodies they make?
AICDA helps B cells alter antibody genes through processes including class switching and somatic hypermutation. These changes let antibody responses become better suited to different immune challenges.
- Common Gene Name
- activation induced cytidine deaminase
- NCBI Gene ID
- 57379
- Chromosome
- 12
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| hyper-IgM syndrome type 2 | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2024-08-28 |
| hyper-IgM syndrome type 2 | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2024-08-28 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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