AKT1
Metabolic System · Insulin Signaling & Glucose Homeostasis
How can AKT1 affect both cell growth and survival?
AKT1 makes a kinase that relays signals by modifying other proteins. The pathways it regulates help cells decide whether to grow, specialize, survive, or undergo programmed death.
- Common Gene Name
- AKT serine/threonine kinase 1
- NCBI Gene ID
- 207
- Chromosome
- 14
Clinical Evidence Status
Disease evidence limited or conflictingTumor or drug-label biomarker context
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (5 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Cowden syndrome 6 | ClinGen gene-disease validity | Limited | Autosomal dominant | View source 2024-11-12 |
| Cowden syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-06 | |
| Proteus syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-06 | |
| Ovarian cancer | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-06 | |
| Capivasertib (1) | FDA labeling biomarker | Label mentions biomarker; actionability not inferred | Oncology | View source |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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