APOL1
Metabolic System · Cholesterol & Lipoprotein Metabolism
Does an APOL1 finding prove that my kidneys are damaged?
APOL1 encodes a protein studied in lipid biology and kidney-disease susceptibility. A risk-associated genotype and existing kidney damage are different findings, so interpretation also requires the specific alleles and clinical assessment.
- Common Gene Name
- apolipoprotein L1
- NCBI Gene ID
- 8542
- Chromosome
- 22
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| focal segmental glomerulosclerosis 4, susceptibility to | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2021-09-28 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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