ATP1A3
Integumentary System · Skin Adnexal Gland Secretion
Why do nerve cells need the ATP1A3 sodium pump?
ATP1A3 encodes a pump component that moves sodium out of neurons and potassium in. Restoring these ion differences helps nerve cells remain capable of electrical signaling.
- Common Gene Name
- ATPase Na+/K+ transporting subunit alpha 3
- NCBI Gene ID
- 478
- Chromosome
- 19
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (3 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| ATP1A3-associated neurological disorder | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2022-05-22 |
| Rapid-onset dystonia parkinsonism | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2024-04 | |
| Alternating hemiplegia of childhood | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2024-04 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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