CALR
Universal Cellular Machinery · Protein Folding & Chaperone Quality Control
What does calreticulin normally do before it is discussed in blood disorders?
CALR encodes calreticulin, a protein involved in protein folding and calcium-related cellular functions. An acquired disease-associated alteration is distinct from the gene's normal housekeeping role.
- Common Gene Name
- calreticulin
- NCBI Gene ID
- 811
- Chromosome
- 19
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (3 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Primary myelofibrosis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2014-09 | |
| Essential thrombocythemia | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2014-09 | |
| 19p13.13 deletion syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2014-09 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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