CATSPER1

Reproductive System · Spermatogenesis & Flagellar Motility

How does calcium help sperm change their swimming pattern?

CATSPER1 makes part of a calcium channel in the sperm tail. Calcium entry through this channel supports the vigorous movement pattern called hyperactivation.

Common Gene Name: cation channel sperm associated 1
NCBI Gene ID: 117144
Chromosome: 11

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 117144
MedlinePlus Genetics — catsper1

Explore supporting evidence (1 records)

Condition or drug	Evidence	Grade / status	Context	Source
CATSPER1-related nonsyndromic male infertility	MedlinePlus related condition	Association type varies; no grade assigned here		View source 2024-04

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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