CAV1
Cardiovascular System · Vascular Endothelial Tone & Vasodilation
Why is CAV1 connected with both blood vessels and body fat?
CAV1 makes caveolin-1, a major component of small pockets in cell membranes. Those structures participate in signaling and material handling across tissues, including blood vessels and fat cells.
- Common Gene Name
- caveolin 1
- NCBI Gene ID
- 857
- Chromosome
- 7
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (5 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| amyotrophic lateral sclerosis | ClinGen gene-disease validity | Limited | Autosomal dominant | View source 2023-12-21 |
| congenital generalized lipodystrophy type 3 | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2025-06-11 |
| lipodystrophy | ClinGen gene-disease validity | Limited | Autosomal dominant | View source 2025-07-16 |
| pulmonary arterial hypertension | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2025-07-30 |
| Congenital generalized lipodystrophy | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-12 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
← Back to Cardiovascular System