CD3E
Immune System · T-Cell Signaling, Differentiation & Checkpoint Tolerance
How does a T cell turn recognition into a response?
CD3E makes one component of the T-cell receptor signaling complex. It helps connect recognition at the cell surface with the internal signals needed for T-cell activity.
- Common Gene Name
- CD3 epsilon subunit of T-cell receptor complex
- NCBI Gene ID
- 916
- Chromosome
- 11
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| immunodeficiency 18 | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2021-01-26 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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