CDK4
Universal Cellular Machinery · Phosphorylation & Kinase Signaling Cascades
What helps a cell pass the checkpoint before copying its DNA?
CDK4 encodes a kinase that works with D-type cyclins to advance the early cell cycle. Inhibitory proteins restrain this activity when conditions do not support division.
- Common Gene Name
- cyclin dependent kinase 4
- NCBI Gene ID
- 1019
- Chromosome
- 12
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| melanoma, cutaneous malignant, susceptibility to, 3 | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2020-01-13 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
← Back to Universal Cellular Machinery