COL11A1
Musculoskeletal System · Chondrogenesis & Articular Cartilage Stability
What helps give cartilage its organized support structure?
COL11A1 makes a component of type XI collagen found in cartilage and other connective tissues. This collagen contributes to the structural framework needed for normal skeletal development and joint support.
- Common Gene Name
- collagen type XI alpha 1 chain
- NCBI Gene ID
- 1301
- Chromosome
- 1
Clinical Evidence Status
Disease evidence limited or conflicting
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (6 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| autosomal dominant nonsyndromic hearing loss | ClinGen gene-disease validity | Moderate | Autosomal dominant | View source 2025-06-18 |
| Stickler syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-04 | |
| Fibrochondrogenesis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-04 | |
| Intervertebral disc disease | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-04 | |
| Osteoarthritis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-04 | |
| Carpal tunnel syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-04 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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