COMT
Nervous System · Synaptic Plasticity & Neurotransmission
Can COMT classify me as a warrior or a worrier?
COMT makes an enzyme that processes catechol compounds involved in signaling and metabolism. Simplified personality labels go beyond what a single COMT finding can establish about a person.
- Common Gene Name
- catechol-O-methyltransferase
- NCBI Gene ID
- 1312
- Chromosome
- 22
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (4 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| 22q11.2 deletion syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2007-09 | |
| Opioid addiction | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2007-09 | |
| Alcohol use disorder | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2007-09 | |
| Fibromyalgia | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2007-09 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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