CPT1A
Metabolic System · Fatty Acid Beta-Oxidation (Mitochondrial & Peroxisomal)
How do long-chain fats become available for energy production in the liver?
CPT1A makes an enzyme needed to direct long-chain fatty acids into mitochondrial processing. This supports the liver's use of fat as fuel, particularly when food-derived energy is limited.
- Common Gene Name
- carnitine palmitoyltransferase 1A
- NCBI Gene ID
- 1374
- Chromosome
- 11
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| carnitine palmitoyl transferase 1A deficiency | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2018-01-23 |
| Carnitine palmitoyltransferase I deficiency | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2025-03 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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