CREBBP

Universal Cellular Machinery · Chromatin Remodeling & Epigenetic Regulation

Why can CREBBP affect many tissues during development?

CREBBP makes a regulator that helps control the activity of numerous genes. Its broad role in cell growth and specialization means developmental effects can span several tissues.

Common Gene Name
CREB binding lysine acetyltransferase
NCBI Gene ID
1387
Chromosome
16

Clinical Evidence Status

Established disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (2 records)
Condition or drugEvidenceGrade / statusContextSource
Rubinstein-Taybi syndromeClinGen gene-disease validityDefinitiveAutosomal dominantView source
2018-04-27
Bladder cancerMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2020-01

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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