CRH

Nervous System · Neuropeptide & Neurotrophin Signaling

How does the brain begin a hormonal stress response?

CRH produces a hormone released by the hypothalamus in response to stress. It signals the pituitary to release ACTH, linking brain activity with downstream hormone production.

Common Gene Name
corticotropin releasing hormone
NCBI Gene ID
1392
Chromosome
8

Clinical Evidence Status

Disease evidence limited or conflicting

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (1 records)
Condition or drugEvidenceGrade / statusContextSource
epilepsyClinGen gene-disease validityRefutedAutosomal dominantView source
2021-09-21

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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