CTSK
Musculoskeletal System · Bone Remodeling
Why do bones need an enzyme that breaks down tissue?
CTSK makes cathepsin K, which is active in bone-resorbing cells called osteoclasts. Controlled removal of old bone is necessary for normal bone remodeling.
- Common Gene Name
- cathepsin K
- NCBI Gene ID
- 1513
- Chromosome
- 1
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| pycnodysostosis | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2022-11-11 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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