CYP19A1

Endocrine System · Steroidogenesis & Nuclear Hormone Signaling

What does CYP19A1 do with testosterone and estrogen?

CYP19A1 encodes aromatase, the enzyme that converts androgens into estrogens. This conversion supports hormone balance in several tissues and cannot be measured simply by reading the gene name on a report.

Common Gene Name
cytochrome P450 family 19 subfamily A member 1
NCBI Gene ID
1588
Chromosome
15

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (3 records)
Condition or drugEvidenceGrade / statusContextSource
Breast cancerMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2014-04
Aromatase deficiencyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2014-04
Aromatase excess syndromeMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2014-04

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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