CYP1A2

Gastrointestinal & Hepatic System · Phase I & Phase II Xenobiotic Detoxification

Does my CYP1A2 result determine exactly how I process caffeine?

CYP1A2 makes a liver enzyme involved in processing several compounds, including caffeine. Its activity is also influenced by environmental and medication factors, so a variant is not a complete measurement of your response.

Common Gene Name: cytochrome P450 family 1 subfamily A member 2
NCBI Gene ID: 1544
Chromosome: 15

Clinical Evidence Status

Tumor or drug-label biomarker context

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 1544

Explore supporting evidence (1 records)

Condition or drug	Evidence	Grade / status	Context	Source
Rucaparib (3)	FDA labeling biomarker	Label mentions biomarker; actionability not inferred	Oncology	View source

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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