DCC

Nervous System · Axonal Guidance & Neurodevelopment

How do growing nerve fibers know which direction to take?

DCC makes a receptor for the guidance signal netrin-1. Their interaction helps direct the extension of axons as the nervous system develops.

Common Gene Name
DCC netrin 1 receptor
NCBI Gene ID
1630
Chromosome
18

Clinical Evidence Status

Established disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (2 records)
Condition or drugEvidenceGrade / statusContextSource
mirror movements 1 and/or agenesis of the corpus callosumClinGen gene-disease validityDefinitiveAutosomal dominantView source
2022-07-26
Congenital mirror movement disorderMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-05

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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