DNAH11

Respiratory System · Mucociliary Clearance & Airway Cilia

How do airway cells move mucus along their surface?

DNAH11 makes part of a dynein motor used by motile cilia. Coordinated ciliary movement helps transport material along tissue surfaces, including the airway lining.

Common Gene Name
dynein axonemal heavy chain 11
NCBI Gene ID
8701
Chromosome
7

Clinical Evidence Status

Actionability report availableEstablished disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (5 records)
Condition or drugEvidenceGrade / statusContextSource
primary ciliary dyskinesia 7ClinGen gene-disease validityDefinitiveAutosomal recessiveView source
2021-10-25
Primary ciliary dyskinesiaMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Heterotaxy syndromeMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Primary Ciliary Dyskinesia (PCD)ClinGen clinical actionabilityScored report; not a validity gradeAdultView source
2023-02-24
Primary Ciliary Dyskinesia (PCD)ClinGen clinical actionabilityScored report; not a validity gradePediatricView source
2023-02-24

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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