DNAH5
Respiratory System · Mucociliary Clearance & Airway Cilia
Why can a cilia gene be relevant beyond the lungs?
DNAH5 encodes a component of the motor machinery inside motile cilia. These structures occur in airways, reproductive tissues, and other locations, so their dysfunction can affect multiple functions.
- Common Gene Name
- dynein axonemal heavy chain 5
- NCBI Gene ID
- 1767
- Chromosome
- 5
Clinical Evidence Status
Actionability report availableEstablished disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (5 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| primary ciliary dyskinesia 3 | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2022-01-07 |
| Primary ciliary dyskinesia | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2025-09 | |
| Heterotaxy syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2025-09 | |
| Primary Ciliary Dyskinesia (PCD) | ClinGen clinical actionability | Scored report; not a validity grade | Adult | View source 2023-02-24 |
| Primary Ciliary Dyskinesia (PCD) | ClinGen clinical actionability | Scored report; not a validity grade | Pediatric | View source 2023-02-24 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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