ENG
Cardiovascular System · Angiogenesis & Lymphangiogenesis
Why might ENG matter in a family with frequent nosebleeds?
ENG makes endoglin, which helps developing blood vessels respond to growth signals. Certain disease-causing variants cause hereditary hemorrhagic telangiectasia, so a confirmed finding can be relevant when nosebleeds accompany a matching personal or family history.
- Common Gene Name
- endoglin
- NCBI Gene ID
- 2022
- Chromosome
- 9
Clinical Evidence Status
Actionability report availableEstablished disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (6 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| juvenile polyposis syndrome | ClinGen gene-disease validity | Limited | Autosomal dominant | View source 2022-12-30 |
| telangiectasia, hereditary hemorrhagic, type 1 | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2022-12-05 |
| Pulmonary arterial hypertension | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2007-02 | |
| Hereditary hemorrhagic telangiectasia | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2007-02 | |
| Hereditary Hemorrhagic Telangiectasia | ClinGen clinical actionability | Scored report; not a validity grade | Adult | View source 2024-03-24 |
| Hereditary Hemorrhagic Telangiectasia | ClinGen clinical actionability | Scored report; not a validity grade | Pediatric | View source 2024-03-24 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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