EPCAM
Universal Cellular Machinery · Cell Adhesion & Extracellular Matrix Architecture
Why is EPCAM associated with cells that line body surfaces?
EPCAM encodes a membrane protein found in epithelial cells, where it supports adhesion and signaling. These cells line organs and cavities, making the protein relevant to how those surfaces are organized.
- Common Gene Name
- epithelial cell adhesion molecule
- NCBI Gene ID
- 4072
- Chromosome
- 2
Clinical Evidence Status
Actionability report availableEstablished disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (3 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Lynch syndrome | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2022-06-20 |
| hereditary breast carcinoma | ClinGen gene-disease validity | Refuted | Autosomal dominant | View source 2023-12-21 |
| Lynch Syndrome | ClinGen clinical actionability | Scored report; not a validity grade | Adult | View source 2023-06-28 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
← Back to Universal Cellular Machinery