FASLG
Universal Cellular Machinery · Apoptosis & Programmed Cell Death
How can one immune cell tell another cell to undergo programmed death?
FASLG makes a surface-associated signal that binds the FAS receptor. This interaction can trigger apoptosis and contributes to the regulation of immune-cell populations.
- Common Gene Name
- Fas ligand
- NCBI Gene ID
- 356
- Chromosome
- 1
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| autoimmune lymphoproliferative syndrome type 1 | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2024-06-07 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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