FLG
Integumentary System · Keratinocyte Cornification & Epidermal Barrier
How does FLG help skin hold on to moisture?
FLG makes profilaggrin, which is processed into proteins and smaller components that support the outer skin layer. This contributes to a functioning skin barrier, but a variant does not determine the severity of someone's skin symptoms.
- Common Gene Name
- filaggrin
- NCBI Gene ID
- 2312
- Chromosome
- 1
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Atopic dermatitis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2017-10 | |
| Alopecia areata | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2017-10 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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