GP1BA

Hematologic System · Platelet Activation & Adhesion

How do platelets first attach at a damaged blood vessel?

GP1BA makes part of a platelet-surface complex that binds von Willebrand factor. This interaction helps platelets engage with an injury site and participate in stopping bleeding.

Common Gene Name
glycoprotein Ib platelet subunit alpha
NCBI Gene ID
2811
Chromosome
17

Clinical Evidence Status

Established disease relationship

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (2 records)
Condition or drugEvidenceGrade / statusContextSource
Bernard-Soulier syndromeClinGen gene-disease validityDefinitiveAutosomal recessiveView source
2020-05-27
platelet-type von Willebrand diseaseClinGen gene-disease validityDefinitiveAutosomal dominantView source
2020-05-27

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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