GSDMD

Immune System · Inflammasome Assembly & IL-1 Maturation

How can a cell's death trigger inflammation?

GSDMD makes gasdermin D, whose activated fragments can form pores in cell membranes. This mechanism contributes to inflammatory cell death called pyroptosis.

Common Gene Name: gasdermin D
NCBI Gene ID: 79792
Chromosome: 8

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 79792
pubmed.ncbi.nlm.nih.gov — 27383986

Explore supporting evidence (0 records)

No additional curated records were matched in this dataset. This does not mean that no evidence exists.

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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