HLA-DRB1

Immune System · HLA & Antigen Processing Presentation

Why are HLA-DRB1 results usually written with detailed allele numbers?

HLA-DRB1 has many forms that influence how protein fragments are presented to immune cells. Those distinctions are needed for allele-specific interpretation, so the broad gene label loses clinically relevant detail.

Common Gene Name
major histocompatibility complex, class II, DR beta 1
NCBI Gene ID
3123
Chromosome
6

Clinical Evidence Status

Drug-response evidence availableTumor or drug-label biomarker context

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (17 records)
Condition or drugEvidenceGrade / statusContextSource
Crohn diseaseMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Idiopathic pulmonary fibrosisMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
NarcolepsyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Psoriatic arthritisMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Idiopathic inflammatory myopathyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Juvenile idiopathic arthritisMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Type 1 diabetesMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Multiple sclerosisMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Hashimoto thyroiditisMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Graves diseaseMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Rheumatoid arthritisMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Autoimmune Addison diseaseMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Alopecia areataMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
Lyme diseaseMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
RosaceaMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2025-09
LapatinibFDA pharmacogeneticsPotential safety or response effectDrug-specific subgroupView source
Lapatinib (4)FDA labeling biomarkerLabel mentions biomarker; actionability not inferredOncologyView source

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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