HSD11B1

Endocrine System · Steroidogenesis & Nuclear Hormone Signaling

How can HSD11B1 change the effects of cortisol in tissues?

HSD11B1 helps interconvert active cortisol and inactive cortisone. This can influence local hormone exposure, but a variant alone cannot diagnose excess cortisol or explain weight gain.

Common Gene Name: hydroxysteroid 11-beta dehydrogenase 1
NCBI Gene ID: 3290
Chromosome: 1

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 3290

Explore supporting evidence (0 records)

No additional curated records were matched in this dataset. This does not mean that no evidence exists.

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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