HSPB1
Universal Cellular Machinery · Protein Folding & Chaperone Quality Control
How can a heat-shock protein protect cells from more than heat?
HSPB1 makes a stress-response protein that helps cells cope with challenges such as inflammation or injury. The heat-shock name describes one trigger within a broader set of protective responses.
- Common Gene Name
- heat shock protein family B (small) member 1
- NCBI Gene ID
- 3315
- Chromosome
- 7
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (3 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Charcot-Marie-Tooth disease axonal type 2F | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2022-08-03 |
| Charcot-Marie-Tooth disease | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2025-03 | |
| Distal hereditary motor neuropathy, type II | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2025-03 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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