HTRA1

Universal Cellular Machinery · Proteolysis & Protease Inhibition

How does HTRA1 help maintain the material surrounding cells?

HTRA1 encodes a protease that breaks down selected extracellular proteins and interacts with signaling pathways. This connects tissue maintenance with the regulation of growth-related messages.

Common Gene Name
HtrA serine peptidase 1
NCBI Gene ID
5654
Chromosome
10

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (2 records)
Condition or drugEvidenceGrade / statusContextSource
Age-related macular degenerationMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2011-06
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2011-06

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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