IGLL1
Immune System · Immunoglobulin & T-Cell Receptor Gene Segments
What helps an immature B cell check its developing receptor?
IGLL1 makes part of the temporary light-chain structure used in the pre-B-cell receptor. Signals from this receptor support the progression of immature cells toward a functional B-cell state.
- Common Gene Name
- immunoglobulin lambda like polypeptide 1
- NCBI Gene ID
- 3543
- Chromosome
- 22
Clinical Evidence Status
Disease evidence limited or conflicting
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (1 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| agammaglobulinemia 2, autosomal recessive | ClinGen gene-disease validity | Moderate | Autosomal recessive | View source 2021-12-21 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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