INS
Metabolic System · Insulin Signaling & Glucose Homeostasis
Does the INS gene actually make insulin?
INS encodes the precursor that pancreatic beta cells process into insulin. The released hormone helps coordinate glucose uptake and use, but an INS variant alone does not measure insulin levels.
- Common Gene Name
- insulin
- NCBI Gene ID
- 3630
- Chromosome
- 11
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (5 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| monogenic diabetes | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2020-05-13 |
| monogenic diabetes | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2020-05-13 |
| Permanent neonatal diabetes mellitus | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2026-01 | |
| Type 1 diabetes | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2026-01 | |
| Maturity-onset diabetes of the young | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2026-01 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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