INSR
Metabolic System · Insulin Signaling & Glucose Homeostasis
What allows a cell to respond when insulin reaches it?
INSR makes the insulin receptor on cell surfaces. Binding insulin activates internal signals that help regulate glucose handling and other metabolic processes.
- Common Gene Name
- insulin receptor
- NCBI Gene ID
- 3643
- Chromosome
- 19
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (5 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Donohue syndrome | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2026-04-08 |
| insulin-resistance syndrome type A | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2026-06-19 |
| Rabson-Mendenhall syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2014-12 | |
| Type A insulin resistance syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2014-12 | |
| Polycystic ovary syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2014-12 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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