ITGA2B
Hematologic System · Platelet Activation & Adhesion
What does ITGA2B contribute to a blood clot?
ITGA2B makes one half of a receptor complex on platelets that pairs with the ITGB3 product. The assembled receptor supports platelet interactions needed to build a stable clot.
- Common Gene Name
- integrin subunit alpha 2b
- NCBI Gene ID
- 3674
- Chromosome
- 17
Clinical Evidence Status
Actionability report availableEstablished disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (4 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| platelet-type bleeding disorder 16 | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2023-11-06 |
| Glanzmann thrombasthenia | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2019-09-04 |
| Glanzmann thrombasthenia | ClinGen clinical actionability | Scored report; not a validity grade | Adult | View source 2022-02-09 |
| Glanzmann thrombasthenia | ClinGen clinical actionability | Scored report; not a validity grade | Pediatric | View source 2022-02-09 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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