ITGB3
Hematologic System · Platelet Activation & Adhesion
Why do ITGB3 and ITGA2B often appear together?
ITGB3 encodes the beta3 component that partners with alphaIIb on platelet surfaces. These proteins work as a receptor pair, so studying one helps explain the clotting function of the other.
- Common Gene Name
- integrin subunit beta 3
- NCBI Gene ID
- 3690
- Chromosome
- 17
Clinical Evidence Status
Actionability report availableEstablished disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (5 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Glanzmann thrombasthenia | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2019-08-28 |
| platelet-type bleeding disorder 16 | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2025-06-04 |
| Osteopetrosis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-09 | |
| Glanzmann thrombasthenia | ClinGen clinical actionability | Scored report; not a validity grade | Adult | View source 2022-02-09 |
| Glanzmann thrombasthenia | ClinGen clinical actionability | Scored report; not a validity grade | Pediatric | View source 2022-02-09 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
← Back to Hematologic System