KL
Renal System · Renal Phosphate & Calcium Handling
Does the Klotho gene provide a reliable longevity score?
KL makes alpha-klotho, a protein with an established role in phosphate regulation, particularly in the kidneys. Interest in aging biology does not make a consumer KL result a validated prediction of lifespan.
- Common Gene Name
- klotho
- NCBI Gene ID
- 9365
- Chromosome
- 13
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Hyperphosphatemic familial tumoral calcinosis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-08 | |
| Kidney stones | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2012-08 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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