KRT5

Integumentary System · Keratinocyte Cornification & Epidermal Barrier

Why are KRT5 and KRT14 often studied as a pair?

KRT5 encodes keratin 5, one partner in the keratin network of epidermal cells. Its partnership with keratin 14 helps the skin withstand routine physical stress.

Common Gene Name
keratin 5
NCBI Gene ID
3852
Chromosome
12

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (2 records)
Condition or drugEvidenceGrade / statusContextSource
Epidermolysis bullosa simplexMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2017-08
Dowling-Degos diseaseMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2017-08

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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