LEP
Metabolic System · Energy Balance, Appetite & Thermogenesis
What does leptin tell the brain about stored body fat?
LEP encodes leptin, a hormone released by fat cells in relation to their stores. The signal helps the body regulate energy balance, but a consumer variant does not directly measure leptin production or responsiveness.
- Common Gene Name
- leptin
- NCBI Gene ID
- 3952
- Chromosome
- 7
Clinical Evidence Status
Tumor or drug-label biomarker context
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Congenital leptin deficiency | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2013-12 | |
| Metreleptin | FDA labeling biomarker | Label mentions biomarker; actionability not inferred | Endocrinology | View source |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
← Back to Metabolic System