LIFR
Reproductive System · Implantation & Placental Function
How does a cell receive the growth signal called LIF?
LIFR makes a receptor that binds LIF and certain other signaling molecules outside the cell. It then sends messages inward that help the cell adjust to its environment.
- Common Gene Name
- LIF receptor subunit alpha
- NCBI Gene ID
- 3977
- Chromosome
- 5
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| obsolete Stüve-Wiedemann syndrome | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2021-07-27 |
| Stüve-Wiedemann syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2016-04 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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