MAP3K1
Reproductive System · Sex Determination & Gonadal Differentiation
How can MAP3K1 influence development before birth?
MAP3K1 makes a signaling protein that works with several partners to regulate cellular pathways. These include pathways involved in establishing sex characteristics during fetal development.
- Common Gene Name
- mitogen-activated protein kinase kinase kinase 1
- NCBI Gene ID
- 4214
- Chromosome
- 5
Clinical Evidence Status
Clinical utility not established here
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (3 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Breast cancer | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-03 | |
| Swyer syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-03 | |
| Langerhans cell histiocytosis | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2015-03 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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