MAPT

Universal Cellular Machinery · Cytoskeletal Organization & Motor Transport

What does tau normally do before it is discussed in dementia research?

MAPT encodes tau, a protein that helps assemble and stabilize microtubules in neurons. These internal fibers support cell shape and the transport of materials along nerve cells.

Common Gene Name
microtubule associated protein tau
NCBI Gene ID
4137
Chromosome
17

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (3 records)
Condition or drugEvidenceGrade / statusContextSource
Frontotemporal dementia with parkinsonism-17MedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2011-03
Idiopathic pulmonary fibrosisMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2011-03
Progressive supranuclear palsyMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2011-03

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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