MC1R

Integumentary System · Melanogenesis & UV Photoprotection

Can MC1R explain why people have different hair and skin colors?

MC1R makes a receptor that influences pigment production in melanocytes. Variants can contribute to coloring differences, although pigmentation also depends on other genes and biological factors.

Common Gene Name
melanocortin 1 receptor
NCBI Gene ID
4157
Chromosome
16

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (2 records)
Condition or drugEvidenceGrade / statusContextSource
Oculocutaneous albinismMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2018-07
MelanomaMedlinePlus related conditionAssociation type varies; no grade assigned hereView source
2018-07

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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