MITF
Integumentary System · Melanogenesis & UV Photoprotection
How does MITF influence pigment-producing cells?
MITF makes a regulator that controls genes needed for the development, survival, and activity of melanocytes. It helps establish the cells that produce pigment rather than serving as the pigment itself.
- Common Gene Name
- melanocyte inducing transcription factor
- NCBI Gene ID
- 4286
- Chromosome
- 3
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (5 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Waardenburg syndrome type 2 | ClinGen gene-disease validity | Definitive | Autosomal dominant | View source 2017-11-21 |
| Waardenburg syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2022-08 | |
| Anophthalmia/Microphthalmia | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2022-08 | |
| Tietz syndrome | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2022-08 | |
| Melanoma | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2022-08 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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