MMP14

Integumentary System · Dermal Extracellular Matrix Organization

How can a cell modify the tissue immediately around it?

MMP14 makes an enzyme positioned on the cell surface that breaks down surrounding matrix components. Local remodeling helps cells change their surroundings as tissues grow and reorganize.

Common Gene Name: matrix metallopeptidase 14
NCBI Gene ID: 4323
Chromosome: 14

Clinical Evidence Status

Clinical utility not established here

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

NCBI Gene — 4323
MedlinePlus Genetics — mmp14

Explore supporting evidence (1 records)

Condition or drug	Evidence	Grade / status	Context	Source
Winchester syndrome	MedlinePlus related condition	Association type varies; no grade assigned here		View source 2013-12

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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