MTR
Metabolic System · Vitamin, Cofactor & One-Carbon Metabolism
How does the body recycle homocysteine into methionine?
MTR makes methionine synthase, the enzyme that carries out that conversion. The resulting methionine supports protein production and other essential chemical processes.
- Common Gene Name
- 5-methyltetrahydrofolate-homocysteine methyltransferase
- NCBI Gene ID
- 4548
- Chromosome
- 1
Clinical Evidence Status
Established disease relationship
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| methylcobalamin deficiency type cblG | ClinGen gene-disease validity | Definitive | Autosomal recessive | View source 2021-07-02 |
| Homocystinuria | MedlinePlus related condition | Association type varies; no grade assigned here | View source 2011-07 |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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