MYC
Universal Cellular Machinery · Transcription Factor Regulation
Why is MYC called a proto-oncogene if normal cells need it?
MYC makes a regulator that helps control gene programs for growth and cell-cycle progression. Excess or dysregulated activity can contribute to cancer, while regulated activity serves normal cellular needs.
- Common Gene Name
- MYC proto-oncogene, bHLH transcription factor
- NCBI Gene ID
- 4609
- Chromosome
- 8
Clinical Evidence Status
Tumor or drug-label biomarker context
These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.
Answer Sources
Explore supporting evidence (2 records)
| Condition or drug | Evidence | Grade / status | Context | Source |
|---|---|---|---|---|
| Polatuzumab Vedotin-piiq (3) | FDA labeling biomarker | Label mentions biomarker; actionability not inferred | Oncology | View source |
| Brentuximab Vedotin (3) | FDA labeling biomarker | Label mentions biomarker; actionability not inferred | Oncology | View source |
Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.
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