NAT2

Gastrointestinal & Hepatic System · Phase I & Phase II Xenobiotic Detoxification

What does being a slow acetylator mean for NAT2?

NAT2 makes an enzyme that chemically modifies certain drugs and other compounds. A slow-acetylator result describes reduced activity in that pathway, with practical implications that depend on the substance involved.

Common Gene Name
N-acetyltransferase 2
NCBI Gene ID
10
Chromosome
8

Clinical Evidence Status

Drug-response evidence availableTumor or drug-label biomarker context

These labels describe available evidence about a gene. They do not classify your variant or recommend a treatment.

Answer Sources

Explore supporting evidence (3 records)
Condition or drugEvidenceGrade / statusContextSource
AmifampridineFDA pharmacogeneticsManagement recommendationDrug-specific subgroupView source
Amifampridine PhosphateFDA pharmacogeneticsManagement recommendationDrug-specific subgroupView source
Amifampridine PhosphateFDA labeling biomarkerLabel mentions biomarker; actionability not inferredNeurologyView source

Source snapshot: 2026-09-09. Consumer text updated: 2026-09-10. Source dates describe the cited records, not a new clinical review.

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